Propulsid

On July 14, 2001, Janssen Pharmaceutica announced it would discontinue marketing, distributing and selling the prescription drug Propulsid (Cisapride), effective immediately. In addition, Janssen advised that, 'patients who are currently prescribed Propulsid are urged to promptly contact their health care providers to discuss alternative treatments.' According to the Food and Drug Administration (FDA) as of December 31, 1999, use of Propulsid was associated with 341 reports of heart rhythm abnormalities including 80 reports of deaths.

Since the drugs approval in 1993, Propulsid's warning label was revised several times (most recently in January 2000), to inform health-care professionals and patients about the drugs risks.

What is Propulsid(Cisapride)?

Propulsid was initially approved by the FDA for use in the US for patients with severe night-time heartburn and gastroesophageal reflux disease (GERD) that did not adequately respond to other therapies.

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