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The Facts About Darvocet®

Feb 7, 2011

Status: Removed from market

Approved Uses: Pain reliever, Fever reducer

Serious Side Effects: Cardiac disorders, Arrhythmia, Bradycardia, Cardiac/respiratory arrest, Congestive arrest, Congestive heart failure (CHF), Tachycardia, Myocardial infarction (MI), Suicide, Death, Lightheadedness, Dizziness, Sedation, Nausea, Vomiting

Propoxyphene (ingredient in Darvocet) is toxic at doses not much higher than the recommend dose because a heart-toxic metabolite accumulates in the body; is somewhat addictive; and has been linked to many thousands of US deaths since 1981, a large proportion of which were likely caused by cardiac toxicity, including the interruption of electrical conduction in the heart.

Even when taken as prescribed, research indicates that norpropoxyphene, the propoxyphene metabolite, can lead to irregular heartbeat in the form of QT prolongation, which extends timing between Q and T waves—two of five electrical impulses measuring heartbeat regularity. This condition is particularly worrisome because QT prolongation does not cause symptoms and, in some cases, can lead to deadly rapid heartbeat known as ventricular tachycardia.

Peterson& Associates, P.C. is dedicated to help patients who have suffered injury from the use of Darvocet®. If you or someone you know has suffered from Darvocet®, call us today.

Categories: Drug Recall

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