Dilantin Lawsuit | Dilantin Lawyer
Recently, a case was settled with pharmaceutical manufacturer Pfizer Inc. on behalf of a family of a nine-year old girl who died as the result of the drug-induced disease, SJS that progressed to TEN, which caused all of her skin to slough off.
Dilantin® Lawsuit
The victim died less than a month after receiving the Pfizer-produced drugs Dilantin® and Flagyl. Dilantin® is an anti-seizure drug and Flagyl is an anti-fungal. Shortly after the administration of the drugs, the patient developed a drug-induced condition known as TEN or toxic epidermal necrolysis. It causes a severe rash and skin sloughing, often followed by infections, blindess or death.
A study compiled by 15 burn centers in the U.S. revealed that more than 20% of TEN cases are believed to be caused by Dilantin® use, with deaths reported in approximately 1 of every 4 cases. Dilantin® is one of the most commonly prescribed anti-seizure drugs in the U.S.
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Dilantin Lawsuit : What is Stevens-Johnson Syndrome?
First described in 1922, Stevens-Johnson Syndrome (SJS) is an immune-complex–mediated hypersensitivity complex that is a severe expression of erythema multiforme. It is known by some as erythema multiforme major, but disagreement exists in the literature. Most authors and experts consider SJS and toxic epidermal necrolysis (TEN) different manifestations of the same disease. For that reason, many refer to the entity as SJS/TEN. SJS typically involves the skin and the mucous membranes. While minor presentations may occur, significant involvement of oral, nasal, eye, vaginal, urethral, GI, and lower respiratory tract mucous membranes may develop in the course of the illness. GI and respiratory involvement may progress to necrosis. SJS is a serious systemic disorder with the potential for severe morbidity and even death. Missed diagnosis is common.
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Symptoms of Stevens Johnson Syndrome
• Rash, blisters, or red splotches on skin
• Persistent fever
• Blisters in mouth, eyes, ears, nose, genital area
• Swelling of eyelids, red eyes
• Conjunctivitis
• Flu-like symptoms
• Recent history of having taken a prescription or over-the-counter medication
(source : stevens-johnson syndrome foundation)
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Epilepsy Drugs Linked To SJS
The FDA announced revisions to the labels of certain epilepsy, bipolar disorder and nerve pain medications to strengthen warnings about potential risk for rare skin disorders such as Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. The FDA has recommended that patients with Asian backgrounds undergo genetic tests before they take the treatments, the Wall Street Journal reports.
The revisions apply to Carbamazepine (the active ingredient in Carbatrol, manufactured by Shire), Tegretol (manufactured by Novartis) and Equetro (manufactured by Validus Pharmaceuticals).
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About SJS :
Stevens Johnson Syndrome (SJS) is a rare skin disorder that can be caused by sever allergic reactions to pharmaceutical drugs that can potentially be fatal.
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Have you developed SJS?
Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are very serious and potentially life-threatening conditions. These conditions can cause death or disable previously healthy people, although rare. SJS is a disease that quickly develops expanding rashes, and can create atypical target lesion, and involvement of the mucous membranes (mouth, eyes, and genital areas).
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